Solarbio

CMTM6 Antibody Blocking Peptide

توضیحات و پروتکل‌های فنی

Master regulator of recycling and plasma membrane expression of PD-L1/CD274， an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes， where it protects PD-L1/CD274 from being targeted for lysosomal degradation， likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279， its receptor on T-cells， ultimately triggering T-cell anergy.

مشخصات و اطلاعات آزمایشگاهی

کد کاتالوگ:

C-K114661P-Ag-500ug

وضعیت تامین:

موجود در انبار سیترا بیوتک

Appearance:

Lyophilized powder

Storage:

Store at -20℃ 2 years.Avoid freeze/thaw cycles.

Unit:

Piece

Source:

Synthetic

تحویل:

یک ماه پس از سفارش

انتخاب مقیاس / حجم بسته‌بندی:

500ug

46800000 تومان