Animal Tissue Optical Clearing Kit

The Animal Tissue Clearing Kit enables convenient and rapid high-quality clearing of whole animals， intact organs， tissue blocks and organoids. Samples processed with this kit are compatible with immunofluorescence， immunohistochemistry， conventional staining， fluorescent staining and bioluminescence assays， supporting three-dimensional imaging of tissue blocks， organoids， intact organs and whole animals. It is widely applied in life science and biomedical research. CUBIC represents a well-established， user-friendly tissue clearing system， and this kit delivers equivalent clearing performance. Solution I in the kit is used for lipid removal and heme decolorization of tissues and organs; Solution II adjusts the refractive index of samples to match that of the surrounding solvent， substantially reducing light scattering and markedly improving optical imaging quality. Product AdvantagesEasy Operation: Samples such as animal tissues and organs are cleared via simple immersion in the kit’s reagents without any specialized instruments or equipment. Superior Clearing Efficiency: Conventional tissue clearing methods only optimize refractive index with limited clearing outcomes. The reagents of this kit efficiently accomplish tissue delipidation and decolorization while precisely matching the refractive index between samples and working solution to reduce light scattering and greatly enhance transmittance for high transparency. Short Clearing Cycle: Complete clearing of mouse tissues and organs is generally achieved within 1-3 weeks. Wide Compatibility: Suitable for clearing discrete animal tissues，intact organs and even whole-body specimens. Fluorescent Protein & Post-staining Compatibility: The formulation preserves the stability of fluorescent proteins throughout processing and prevents denaturation and fluorescence quenching of common reporters including EGFP，EYFP and mCherry，enabling subsequent fluorescent staining.